Respiratory syncytial virus as a trigger of a pulmonary hypertensive crisis after operative correction of aortic coarctation
We discuss a 9-month-old male baby, submitted to surgery for correction of aortic coarctation, who showed severe bronchospasm, hypoxaemia, and cardio-respiratory arrest, and who died on the fifth postoperative day. The autopsy revealed histological signs of severe pulmonary vasoconstriction, possibly as a consequence of hypoxaemia secondary to bronchiolitis due to infection with the respiratory syncytial virus. This supposition was confirmed when viruses were detected in pulmonary tissue by immunohistochemistry and electron microscopy.(Accepted September 14 2006)
Key Words: Congenital heart disease; hypoxia; cardiac postoperative outcome.
c1 Correspondence to: Jussara B. Castelli, Laboratório de Anatomia Patológica, Instituto do Coração – Hospital das Clínicas da FMUSP, Av. Dr Enéas Carvalho de Aguiar, 44, São Paulo – SP – Brazil, CEP 05403000. Tel: +55 11 3069 5077; Fax: +55 11 3069 5279; E-mail: email@example.com