Molecular epidemiology of norovirus infections in children and adults: sequence analysis of region C indicates genetic diversity of NVGII strains in Kolkata, India

Epidemiology and Infection

Epidemiology and Infection / Volume 139 / Issue 06 / June 2011, pp 910-918
Copyright © Cambridge University Press 2010
DOI: http://dx.doi.org/10.1017/S0950268810001731 (About DOI), Published online: 19 July 2010

Table of Contents - June 2011 - Volume 139, Issue 06

Gastrointestinal infections

Molecular epidemiology of norovirus infections in children and adults: sequence analysis of region C indicates genetic diversity of NVGII strains in Kolkata, India

Article author query
nataraju sm [PubMed] [Google Scholar]
pativada m [PubMed] [Google Scholar]
chatterjee d [PubMed] [Google Scholar]
nayak mk [PubMed] [Google Scholar]
ganesh b [PubMed] [Google Scholar]
bhattacharya mk [PubMed] [Google Scholar]
ramamurthy t [PubMed] [Google Scholar]
ganguly s [PubMed] [Google Scholar]
saha dr [PubMed] [Google Scholar]
rajendran k [PubMed] [Google Scholar]
ghosh m [PubMed] [Google Scholar]
kobayashi n [PubMed] [Google Scholar]
krishnan t [PubMed] [Google Scholar]

S. M. NATARAJU^a1, M. PATIVADA^a1, D. CHATTERJEE^a1, M. K. NAYAK^a1, B. GANESH^a1, M. K. BHATTACHARYA^a2, T. RAMAMURTHY^a3, S. GANGULY^a4, D. R. SAHA^a5, K. RAJENDRAN^a6, M. GHOSH^a7, N. KOBAYASHI^a8 and T. KRISHNAN^a1 ^c1

^a1Division of Virology, National Institute of Cholera and Enteric Diseases (NICED), Beliaghata, Kolkata, West Bengal, India

^a2Division of Clinical Medicine, National Institute of Cholera and Enteric Diseases (NICED), Beliaghata, Kolkata, West Bengal, India

^a3Division of Microbiology, National Institute of Cholera and Enteric Diseases (NICED), Beliaghata, Kolkata, West Bengal, India

^a4Division of Parasitology, National Institute of Cholera and Enteric Diseases (NICED), Beliaghata, Kolkata, West Bengal, India

^a5Division of Electron Microscopy, National Institute of Cholera and Enteric Diseases (NICED), Beliaghata, Kolkata, West Bengal, India

^a6Division of Data Management, National Institute of Cholera and Enteric Diseases (NICED), Beliaghata, Kolkata, West Bengal, India

^a7Infectious Diseases & Beliaghata General (ID&BG) Hospital, Kolkata, West Bengal, India

^a8Department of Hygiene, Sapporo Medical University School of Medicine, Sapporo, Japan

SUMMARY

Faecal specimens of diarrhoea cases (n=2495, collected between November 2007 and October 2009) from Infectious Diseases and Beliaghata General (ID&BG) Hospital, Kolkata, India, were screened by RT–PCR using specific primers targeting region C of the capsid gene of noroviruses (NoVs) to determine the seasonal distribution and clinical characteristics of NoVs associated with diarrhoea. NoV infection was detected in 78 cases, mostly in children aged <2 years. In 22/78 positive cases, the virus was detected as the sole agent; others were as mixed infections with other enteric pathogens. Sequencing of NVGII strains showed clustering with GII.4 NoVs followed by GII.13 and GII.6 NoVs. Clinical characteristics of the diarrhoeic children and adults in Kolkata indicated that NoV infections were detected throughout the year and were associated with a mild degree of dehydration.

(Accepted June 25 2010)

(Online publication July 19 2010)

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Correspondence:

^c1 Author for correspondence: Dr T. Krishnan, Scientist-D, Division of Virology, National Institute of Cholera & Enteric Diseases, P-33, C.I.T. Road, Scheme-XM, Beliaghata, Kolkata-700010, West Bengal, India. (Email: drtriveni.krishnan@gmail.com)

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<div style="background: #FFFFFF; margin: 0 10px 10px 0; padding: 0 10px 0 0; text-align: left; font-family: Arial, Helvetica, sans-serif; line-height: 1em;"><div style="font-size: 11px; padding: 0px 0px 10px 0px; font-weight:bold; color: #045989;">Molecular epidemiology of norovirus infections in children and adults: sequence analysis of region C indicates genetic diversity of NVGII strains in Kolkata, India</div><div style="font-size: 11px;"><b>
					S. M. NATARAJU,
					M. PATIVADA,
					D. CHATTERJEE,
					M. K. NAYAK,
					B. GANESH,
					M. K. BHATTACHARYA,
					T. RAMAMURTHY,
					S. GANGULY,
					D. R. SAHA,
					K. RAJENDRAN,
					M. GHOSH,
					N. KOBAYASHI
					 and T. KRISHNAN (2011).	</b><br /><a href="http://journals.cambridge.org/action/displayJournal?jid=HYG">Epidemiology and Infection</a>, <a href="http://journals.cambridge.org/action/displayJournal?jid=HYG&volumeId=139&bVolume=y#loc139>
				 ">Volume 139</a>, <a href="http://journals.cambridge.org/action/displayIssue?jid=HYG&volumeId=139&issueId=06&seriesId=0">Issue06</a>, June 2011 pp 910-918<br/>
<a href="http://journals.cambridge.org/action/displayAbstract?aid=8266588">http://journals.cambridge.org/action/displayAbstract?aid=8266588</a></div></div>

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Molecular epidemiology of norovirus infections in children and adults: sequence analysis of region C indicates genetic diversity of NVGII strains in Kolkata, India

S. M. NATARAJU, M. PATIVADA, D. CHATTERJEE, M. K. NAYAK, B. GANESH, M. K. BHATTACHARYA, T. RAMAMURTHY, S. GANGULY, D. R. SAHA, K. RAJENDRAN, M. GHOSH, N. KOBAYASHI and T. KRISHNAN June 2011
Epidemiology and Infection, ,Volume139, Issue06, June 2011 pp 910-918
http://journals.cambridge.org/10.1017/S0950268810001731

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Epidemiology and Infection

Gastrointestinal infections

Molecular epidemiology of norovirus infections in children and adults: sequence analysis of region C indicates genetic diversity of NVGII strains in Kolkata, India

S. M. NATARAJUa1, M. PATIVADAa1, D. CHATTERJEEa1, M. K. NAYAKa1, B. GANESHa1, M. K. BHATTACHARYAa2, T. RAMAMURTHYa3, S. GANGULYa4, D. R. SAHAa5, K. RAJENDRANa6, M. GHOSHa7, N. KOBAYASHIa8 and T. KRISHNANa1 c1

S. M. NATARAJU^a1, M. PATIVADA^a1, D. CHATTERJEE^a1, M. K. NAYAK^a1, B. GANESH^a1, M. K. BHATTACHARYA^a2, T. RAMAMURTHY^a3, S. GANGULY^a4, D. R. SAHA^a5, K. RAJENDRAN^a6, M. GHOSH^a7, N. KOBAYASHI^a8 and T. KRISHNAN^a1 ^c1