Epidemiology and Infection

Table of Contents - 2005 - Volume 133, Issue 03  


Serological and virological features of dengue fever and dengue haemorrhagic fever in Thailand from 1999 to 2002

S. ANANTAPREECHA a1c1, S. CHANAMA a1, A. A-NUEGOONPIPAT a1, S. NAEMKHUNTHOT a1, A. SA-NGASANG a1, P. SAWANPANYALERT a1 and I. KURANE a2
a1 National Institute of Health, Department of Medical Sciences, Ministry of Public Health, Nonthaburi, 11000, Thailand
a2 Department of Virology I, National Institute of Infectious Diseases, Toyama, Shinjuku-ku, Tokyo 162–8640, Japan

Article author query
anantapreecha s   [PubMed][Google Scholar] 
chanama s   [PubMed][Google Scholar] 
a-nuegoonpipat a   [PubMed][Google Scholar] 
naemkhunthot s   [PubMed][Google Scholar] 
sa-ngasang a   [PubMed][Google Scholar] 
sawanpanyalert p   [PubMed][Google Scholar] 
kurane i   [PubMed][Google Scholar] 

Abstract

Serological and virological features of dengue fever (DF) and dengue haemorrhagic fever (DHF) in Thailand were analysed in 2715 patients from 1999 to 2002. The illness was caused by DEN-1 in 45%, DEN-2 in 32%, DEN-3 in 18% and DEN-4 in 5% of patients. Almost all of the DHF cases caused by DEN-2 and DEN-4 were in secondary infection, while approximately 20% of the DHF cases caused by DEN-1 and DEN-3 were in primary infection. Male[ratio]female ratio and age distribution were not different among four serotypes in primary and secondary infections. These results indicate that DEN-1 and DEN-3 induce DHF in both primary and secondary infections, and suggest that DEN-2 and DEN-4 in Thailand are less likely to cause DHF in primary infections.

(Accepted November 20 2004)


Correspondence:
c1 National Institute of Health, Department of Medical Sciences, Ministry of Public Health, 88/7, Tivanond Road, Muang, Nonthaburi, 11000, Thailand. (Email: surapee@dmsc.moph.go.th)

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