Working memory deficits in chronic fatigue syndrome: Differentiating between speed and accuracy of information processing
To examine the relative influence of speed of information processing versus working memory ability, CFS participants with psychiatric comorbidity (CFS–Psych) and CFS without a psychiatric history (CFS–noPsych) were examined on tests of visual and auditory processing speed and visual and auditory working memory. Compared to healthy controls (HC) and a group of participants with rheumatoid arthritis (RA), the CFS–noPsych group displayed significantly reduced performance on tests of information processing speed, but not on tests of working memory. No significant differences were observed between the CFS–Psych group and any other group in the study. The implications of group heterogeneity on the understanding of cognitive impairment in CFS are discussed. (JINS, 2004, 10, 101–109.)(Received October 7 2002)
(Revised March 31 2003)
(Accepted May 13 2003)
Key Words: Processing speed; Working memory; Cognition.
c1 Reprint requests to: John DeLuca, Ph.D., Neuropsychology and Neuroscience Laboratory, Kessler Medical Rehabilitation Research and Education Corporation, 1199 Pleasant Valley Way, West Orange, NJ 07052. E-mail: Jdeluca@kmrrec.org