Cardiology in the Young

Brief Reports

Amiodarone-induced pulmonary toxicity in an adolescent

Shyam S. Kotharia1 c1, Sharada Balijepallya1 and Karuna Tanejaa2

a1 Department of Cardiology, All India Institute of Medical Sciences, New Delhi, India

a2 Department of Cardiac-Radiology, All India Institute of Medical Sciences, New Delhi, India

Abstract

We report amiodarone-induced pulmonary toxicity in an 18-year-old who had undergone corrective surgery for tetralogy of Fallot 4 years earlier, and was treated with amiodarone because of recurrent malignant postoperative ventricular tachyarrhythmias. Toxicity was recognized on the basis of clinical features, chest X-ray, high-resolution contrast enhanced computerized tomography, and resolution of the findings subsequent to withdrawal of amiodarone and treatment with steroids. pulmonary toxicity due to amiodarone, as far as we know, has not been reported in children and young adults, and its occurence even in young adults requires wider appreciation.

(Accepted February 06 1998)

Correspondence:

c1 Dr. SS Kothari, MD, DM, Department of Cardiology, Cardiothoracic Centre, All India Institute of Medical Sciences, New Delhi – 110 029, India. Tel: 661123–2824851; Fax 91–011–686–2663; e-mail: kothari@medinst.ernet.in

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