Zygote

Article

Oocyte reaction to penetrating sperm

G. Galeatia1

a1 Istituto di Fisiologia Veterinaria-Ozzano Emilia, Bologna, Italy

Before fertilisation the egg is metabolically quiescent and its nucleus is arrested at metaphase of the second meiosis. After sperm-egg fusion, the arrested nucleus resumes meiosis, and then changes into the female pronucleus. Such a sequence of morphological and biochemical events is called “activation”. The inital responses of the egg to activation by the sperm include cortical granule exocytosis and resumption of meiosis.

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